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Product Info Summary
| SKU: | A01170 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC |
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Product info
Product Name
Anti-Collagen alpha-1(VII) chain COL7A1 Antibody
View all Collagen VII Antibodies
SKU/Catalog Number
A01170
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Collagen alpha-1 (VII) chain COL7A1 Antibody catalog # A01170. Tested in ELISA, IF, IHC applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Collagen alpha-1(VII) chain COL7A1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01170)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human COL7A1
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01170 is reactive to COL7A1 in Human, Mouse
Applications
A01170 is guaranteed for ELISA, IF, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
295.22kDa
Background of Collagen VII
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.
ShunJiang Yu, J. Biol. Chem., May 2003; 278: 19597 - 19602.
TT Chen, Mol. Cell. Biol., Jun 1997; 17: 3056 - 3064.
Oscar B. Goodman, J. Biol. Chem., Oct 1995; 270: 23768.
Didier Jean, J. Biol. Chem., Jun 1998; 273: 16501
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For COL7A1 (Source: Uniprot.org, NCBI)
Gene Name
COL7A1
Full Name
Collagen alpha-1(VII) chain
Weight
295.22kDa
Alternative Names
Collagen 7; collagen alpha-1(VII) chain; collagen VII, alpha-1 polypeptide; collagen, type VII, alpha 1; Collagen-7; EBD1; EBDCT; EBR1; epidermolysis bullosa, dystrophic, dominant and recessive; LC collagen; long chain collagen; Long-chain collagen COL7A1 EBD1, EBDCT, EBR1, NDNC8 collagen type VII alpha 1 chain collagen alpha-1(VII) chain|LC collagen|collagen VII, alpha-1 polypeptide|collagen, type VII, alpha 1|long-chain collagen
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on COL7A1, check out the COL7A1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for COL7A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Collagen alpha-1(VII) chain COL7A1 Antibody (A01170)
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No publications found for A01170
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Customer Reviews
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